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peterlindsey

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About peterlindsey

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  • Birthday 01/11/1993

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  1. Alzheimer’s & Parkinson’s figure amongst the most horrendous neurodegenerative diseases that cause changes in the brain and create impediments to its normal functioning. The symptoms of Alzheimer’s include; partial or complete memory loss, inability to understand and respond, inability to focus and inability to act in other similar situations. On the other hand, Parkinson’s causes decay of neurons that exist on the surface of the brain cells. Neurons act as messengers between the brain and the organs, limbs and parts of our body. They convey messages to them to perform various functions, like hearing, eating, moving, sleeping, understanding & the other. In simple words, both of these two, cripple a person lifelong. Just think of a person who has Alzheimer’s or Parkinson’s conditions and imagine about the nightmare that he passes through. And so on, making a mentally or bodily crippled patient sits on a chair during the day & on the bed in the night and managing his needs has been much beyond a just ordeal that the attendants have to undergo for a period unknown to them. As of today, there is no such conventional medicinal treatment that may stop the further decay or regenerate or rejuvenate the neurons or the brain cells already decayed due to these diseases. This is what makes the Alzheimer’s & Parkinson’s as one of the most dreadful diseases. Unfortunately, both of these are affecting over 5 million people in America alone. Alzheimer’s & Parkinson’s: What Happens? Alzheimer’s is the most common neurocognitive disorder of dementia. The disease is degenerative in nature. Mostly, people of the age 60 and above get affected by the Alzheimer’s. An Alzheimer’s patient has to face a multitude of problems. There is a significant shift in his behavior. He is unable to complete even a simple task. He would not remember the place he had visited very recently then or the person with whom he was talking or the matter of the conversation. He fails to understand the things & the way to handle them. He can neither understand, nor respond. Parkinson’s is a slow progressing disease. At the early stages, the symptoms are not so critical and the patient ignores them. As time rolls by, the condition of the patient goes on worsening. And when he decides to consult a physician, it’s too late. By that time, about 80% of the active neurons & brain cells have already decayed & there can’t be a come back. The patient faces tremors in the legs and shaking of the hands & limbs. He feels difficulty in maintaining the balance while standing or walking. He needs a full-time assistant for all the activities even related to his person. Hallucinations and visionary illusions are common among the Parkinson’s patients. They feel and see which is not there. They are afraid of what does not exist. Despite administering the best available medicines, the patient hardly responds to them or shows any signs of improvement. Can Medical Cannabis Be Helpful in the Treatment of Alzheimer’s & Parkinson’s? Yet, contrary to the situation in conventional medical practices, Medical Marijuana Doctors see a ray of new hope in the cannabis. They are hopeful that this ill-famed herb has some of the inherent medicinal properties and contain some compounds (CBC, CBD & THC) that have one-to-one proximity to our internal endocannabinoid mechanisms (ECS) and carries the potential to put the brain-related disorders, including Alzheimer's & Parkinson's on the right track. When the actual reasons behind Alzheimer’s & Parkinson’s remains a mystery, the marijuana doctors are confident that this herb has the potentials to stop progressions of their conditions. Both of these diseases are directly related to the brain. It’s beyond doubts that cannabis effects on the brain most. It’s also not disputed in the scientific-research and medical circles that cannabis is not as bad as it carries the ill fame and has some of its inherent medicinal properties. Both scientific fields have already established some of its beneficial effects on brain-related mental ill-health conditions. Some of these factors lead us to the discourse, whether cannabis could add a little benefit or contribute significantly to the treatment of the Alzheimer’s & Parkinson’s specifically when currently, absolutely no conventional medicine is effective. One of the major causes of the Parkinson’s is the decay of neurons, which act as messengers and convey signals from the nervous system to the vital organs and other parts of the body. “Cannabinoids are a unique class of chemical compounds incorporating plant-derived cannabinoids (the active components of Cannabis sativa), the endogenous cannabinoids and synthetic cannabinoid ligands, and these compounds are becoming increasingly recognized for their roles in neural developmental processes. Indeed, cannabinoids have clear modulatory roles in adult neurogenesis, probably through activation of both CB1 and CB2 receptors. In recent years, a large body of literature has deciphered the signalling networks involved in cannabinoid-mediated regulation of neurogenesis. This timely review summarizes the evidence that the cannabinoid system is intricately associated with neuronal differentiation and maturation of NPCs and highlights intrinsic/extrinsic signalling mechanisms that are cannabinoid targets.” The ECS is the largest cell receptor mechanism in our body. This mechanism controls the most important functioning part of our internal system. The researchers have established that ECS system was badly affected when neurons had died or decayed. They have further established that cannabis when consumed, cannabinoids (CBC, CBD & THC) available in it, engage this (ECS) system. Studies conducted in the laboratories on mice showed that CBD compounds in cannabis could stop decay of healthy cells. The researchers have also found that CBD helps in the growth and development of the brain. Studies on rats given a cannabinoid showed that cannabis stimulates the growth of new brain cells. Similar studies conducted by the Canadian researchers established that a regular use of cannabis caused neurons to regenerate in the hippo campus, an area that controls mood and emotions. One main factor that contributes to the decay of cells and neurons is the inflammation in the brain. The cannabinoids in the cannabis have anti-inflammatory properties. Active compounds available in cannabis (THC, CBD & CBC) effect against both amyloid beta proteins and inflammation. They reduce and control the inflammation in the brain and consequently, stop the decay of the neurons. When no conventional medicine is effective, patients trying on cannabis for the treatment of Alzheimer’s & Parkinson’s have nothing to lose, but only to gain. Medical cannabis at least have the capacity to provide relief against pains, stiffness, jerks, trembles, spasms, sleeplessness, inflammation (in the brain) and other conditions that are related to these two diseases.
  2. Let’s be grateful to Marijuana because depression can now be effectively managed with its amazing benefits! I also suffered from depression helped me a lot. Nice post!
  3. Since long, scientists have been struggling to find out some alternative medicines that are safe and could replace some of the existing conventional formulations. One of the main reasons for this endeavor is, most of the conventional medicines result in side effects. They create additional multifarious health problems irrespective of whether the patient recovered from the disease for which he had taken the medicines, or not. In the realm of plants & herbs, cannabis is best known for its property that gets us “High” while we smoke recreationally or Vape medically. But in its kitty, there also exists a species with the compound that minds only health & health, nothing else. It’s CBD. On this day, media channels were rejoiced to break the news that the FDA gave its assent to Epidiolex, the first CBD oil infused oral formulation that the drug authority found useful in the treatment of severe conditions of epilepsy-related 2-critical seizures. That way, cannabis proved that it’s much beyond just a euphoric drug and is extensively beneficial in therapeutic use. Due to its unique medicinal properties, the use of CBD oil & extracts of cannabidiol has increased many folds during the recent years. What’s Epilepsy? Epilepsy, by & large, is a neurological disorder resulting out of dysfunction of our Central Nervous System. It’s a condition that causes recurrent seizures at irregular intervals, time & again due to abnormal electrical discharges from the brain. Such conditions occur due to illnesses of the brain & inflammation of neurons-the brain cells, injuries, overdose or side effects of strong medicines, etc. Epilepsy could also be due to abnormal development & growth of the brain and prenatal abnormalities. An epilepsy patient may have severe seizures, unusual behavior and loss of consciousness during the attack. While under an attack of seizures, the patient may have stony eyes, trembling of the hands, legs and neck. In fact, entire body of the patient looks like shivering, jerking and collapsing. The patient has absolutely no control over it. Sometimes, the mouth stays open & spits the froth. Epilepsy is one of several life-threatening diseases that affect the people crossing barriers of age. In America, approximately, 5,000 people die of epilepsy every year. This includes sudden deaths (SUDEP) that occur immediately after an epilepsy attack, but the reasons have not cropped up yet and remain shrouded under a mystery. Besides direct deaths due to epilepsy, this neurological disorder also causes deaths in other ways. The suicide rate is higher by about 22 % in the patients having epilepsy conditions than others. Epilepsy patients are always prone to accidents, sometimes fatal. CBD Oil & Seizures The story of using CBD for seizures relates to Charlotte, the little girl who had got a first life-threatening attack of seizures when she was hardly 3-months old. At the age of 5, the doctors attending upon her raised their hands and told her parents that there is nothing left with them to help the little girl. When all conventional medicines had failed, CBD worked, and she fully recovered from the worst type of seizures attacks. Cannabis enjoys a time-tested and scientifically proven record of its beneficial effects on the brain. Scientists have been able to discover about 70 chemical compounds in the cannabis, known as cannabinoids. These include THC & CBD. Most of these have the same structure as endogenous cannabinoids in our body have. As such, cannabinoids in the cannabis and the body, both work the same way. While THC is widely popular as a psychoactive substance, the CBD not. Medicinal properties of THC had been recognized long ago, but in the case of CBD, it took years. It’s only during the last decade when the scientists found that CBD could be more useful in the treatment of brain-related disorders because it does not have euphoric effects. CBD has some exceptional medicinal properties that promise to deliver the results in the treatment of seizures, beyond expectations. The possession or use of cannabis or marijuana in any form is illegal and a completely prohibited substance at the Federal level. Despite this fact, the FDA, recognizing the potentials of the CBD, has granted their approval to cannabidiol infused medicine, “Epidiolex”. This is an oral solution, a first phytocannabinoid derived medicine. This CBD infused drug has been approved for “seizures associated with Lennox- Gastaut Syndrome or Dravet Syndrome, two rare, severe childhood-onset epilepsies. A research report in the Journal of Epilepsy Research, published online in the PMC, US National Library of Medicine, National Institute of Health. “THC has psychoactive properties exerted through its binding of the cannabinoid receptor (CBR) whereas CBD is a CBR antagonist. The inhibition of epilepsy by CBD may therefore be caused by various mechanisms, although the detailed mechanisms of CBD actions have not yet been well defined. In most studies, trial doses of CBD were 2–5 mg/kg/day. Several such studies have shown that CBD does have efficacy for treatment of epilepsy.” Strains Useful in Seizures: There are over 700 species of hybrid and organic cannabis. Marijuana strains with higher content of CBD are more effective in the treatment of seizures. 1. ACDC: ACDC is one of the cannabis species that has the least THC content and the highest CBD. Its has CBD as high as 24-25 and THC as low as only 0.5- 1%. As such, this strain is mainly used for medicinal purpose or treatment of such conditions where the CBD is effective and THC has no role to play. 2. Corazon: Carson is one of the latest hybrid cannabis strains that matches ACDC in terms of the CBD content which is as high as 23%. It has THC up to 3 %. The strain could be useful in the treatment of epilepsy & seizures. 3. Charlotte’s Web: It’s an Indica- Sativa 60:40 strain. It was one of the strains that were first used for the treatment of epilepsy & seizures. Like ACDC, Charlotte’s Web has a high CBD content of about 17% and THC as low as only 1%. 4. Harle - Tsu: Harle - Tsu is an Indica- Sativa 60 : 40 strain that contains CBD as high as 22% and THC as low as 1%. Its prominent property is, it sends us into a relaxing position and alleviates the pain, if any. Its CBD content is useful for the treatment of epilepsy. 5. Ringo’s Gift: It’s a Sativa - Indica 60 : 40 strain. This strain also has CBD content as much as 15% and THC as low as 1%. Besides useful in the treatment of epilepsy & seizure, Ringo’s Gift is also useful in other critical conditions like tremors, anxiety, inflammation & spasms etc. As of now, it’s well-established that CBD Oil is highly effective in the treatment of seizures and other neurological disorders. In the next few years, we hope to see this natural extract as a new alternative medicine completely replacing the salt based conventional medicines. There are are over 700 varieties of cannabis. Selecting a right strain is not simple because their medicinal properties vary from strain to strain.
  4. Cannabis is such an amazing plant where cannabinoids and terpenes work synergistically, and this is collectively called full-spectrum extract. While THC has euphoric effects, CBD and terpenes are known for their non-psychoactive effects. Hence, the impact of a particular cannabis strain can vary dramatically depending upon the ratio of the two active cannabinoids. You might have noticed while visiting a dispensary that the cannabis products are organized by Indica or Sativa flavor profile, price per gram, and also via THC:CBD content. But, still very few people have any information about the benefits of the correct THC:CBD ratio. Hence, instead of just focussing on the dosage of cannabis-based on milligrams or percentage, people are considering ratios as the basis for choosing a strain for medical purposes. CBD vs. THC Marijuana contains over 100 types of chemical compounds called cannabinoids. Out of these cannabinoids, CBD and THC are known for their interaction with the body’s endocannabinoid system receptors. They both have different medicinal properties as well as effects on the body. The difference lies in the way they interact with the receptors in the body. While THC binds CB1 receptor favorably, CBD acts as an antagonist to the receptors and also partially blocks the CB1 receptors, thus reduces the euphoric effects of the THC molecules. THC is known for its euphoria while acting as an anti-inflammatory, anti-emetic, and an analgesic. However, CBD shares some of these properties but, also is known for its anti-seizure, anti-anxiety and anti-psychotic properties. Some studies even have reported that CBD is thought to enhance anti-cancer and pain reducing properties of THC. Therefore, depending on your particular condition, you will respond to the different CBD:THC ratios present in the strains. CBD:THC ratios and their benefits CBD:THC 0:1 This is a THC dominant strain where the person will experience intense psychoactive effects. The strains with such ratios are known for uplifting the moods, thus making the person happy. These strains can help induce appetite, reduce inflammation with relaxing effects. Strains with high THC content are Gorilla Glue by Zamnesia with THC content of 25%, and Girl Scout Cookies is loaded with 22% of THC CBD:THC 1:2 This type of strain produces a calming sensation with reduced cases of anxiety. Thus, these type of strains can significantly reduce the euphoric effects of THC with the help of CBD which acts as an antagonist. These strains can help in dealing with the number of conditions like chronic pain, anxiety, stress, insomnia, migraines, and muscle spasms with the help of synergistic benefits that THC and CBD provide. Strains with less THC with counterbalancing CBD levels are Blue Widow, OG Kush. CBD:THC 1:1 Research so far supports strains with this kind of chemical makeup as these strains provides the most effective medicinal properties for a different number of disorders and their associated symptoms like insomnia, fibromyalgia, autism, chronic pain, spasticity, reduced appetite, and skin diseases. This kind of ratio provides the maximum relaxing effects with minimal euphoria. Strains known for this particular ratio are Cannatonic, Sweet Tooth Auto, Critical Mass CBD. CBD:THC 2:1 or 3:1 This type of strain is ideal for the patients who wish to avoid the euphoric effects of THC. This ratio is suitable to combat autoimmune disorders, gastrointestinal issues like Crohn’s and colitis, arthritis, and psoriasis. The strains which are known for their calming effects with high CBD content are Kama Kush CBD, CBD Critical Cure, and Cheese Autoflowering. CBD:THC 1:0 This is the CBD dominant strain with enormous medicinal potential. The ratio is very rare in reality. However certain strains are close to this ratio such as CBD Therapy with 10% CBD and just 0.5% THC, Candida (CD-1) with 20% CBD and only 1% THC. These findings support the need for the knowledge about the best ratio for effective treatment. It is advocated to start with a small dose of CBD rich ratio and gradually adding the THC content to get maximum therapeutic benefits. Just like any other pharmaceutical drug, which requires a prescription, one must consult cannabis specialists rather than thinking about self-treatment with marijuana.
  5. peterlindsey

    CBD oil: a beginner's guide

    Cannabis oil is a thick, sticky substance composed of cannabinoids, such as THC and CBD, which is obtained from cannabis flowers using a solvent extraction procedure. It is the most concentrated form of cannabis products, which makes cannabis oil the most powerful. The oil can be vaporized into the lungs, ingested orally, applied topically or used as a suppository. According to my research. I also found that cannabis was useful in treating many health disease in particular. Studies in mice and rats showed that Cannabinoids block the growth of cancer cells. THC & CBD choke the further growth of the blood vessels that supply blood to the cancer cells. This way, CBD cuts off the source of energy that helps the cancer cells to grow and expand. It can also be mixed with creams or salves for beauty treatments and other external uses. So that CBD is the best remedy for cancer patients.
  6. peterlindsey

    CBD oil

    Cannabis oil is a thick, sticky substance composed of cannabinoids, such as THC and CBD, which is obtained from cannabis flowers using a solvent extraction procedure. It is the most concentrated form of cannabis products, which makes cannabis oil the most powerful. The oil can be vaporized into the lungs, ingested orally, applied topically or used as a suppository. According to my research. I also found that cannabis was useful in treating many health diseases i.e cancer, anxiety, insomnia. Studies in mice and rats showed that Cannabinoids block the growth of cancer cells. THC & CBD choke the further growth of the blood vessels that supply blood to the cancer cells. This way, CBD cuts off the source of energy that helps the cancer cells to grow and expand. So that CBD is the best remedy for cancer patients. Here I would also suggest you before taking any dose of cannabis, consult with a Licensed cannabis doctor who could share proper medical prescription.
  7. The reasoning behind all this comes down to the way the compounds of cannabis interact with the body. When you eat cannabis, it has to go through the digestive system. During the process of absorption, THC passes through the liver, where it is converted into a much more powerful form. Delta-9 THC (normal THC) becomes 11-hydroxy-THC, which can pass the blood-brain barrier with much more ease and a much stronger punch! When you inhale cannabis, either in the form of smoke or vapor, the compounds are absorbed directly into your blood through the lungs. This causes the THC to bypass the liver, and head straight for the brain, resulting in a much more instantaneous, but less powerful high. It is worth noting that when you smoke weed, the THC that doesn’t make it across the blood-brain barrier on the initial pass gets a ride through the bloodstream as it makes its way back around the body. On its journey, it will come to the liver, where, much in the same as when you eat it, it will be converted into 11-hydroxy-THC. This causes you to feel the effects of both forms of THC, once it makes its way back around to the brain. The main difference between eating and smoking is that ALL of the THC you consume when eating is converted into 11-hydroxy-THC, whereas only a portion of the THC from smoking is. Smoked cannabis tends to peak in strength after 10 minutes, and then rapidly dissipate over the next 30 minutes to an hour. So through titration, you can keep yourself on a level over a period of time. This is not possible when you eat marijuana, you get it all in one go. However, as you get to know your stash and the strength of your preparation you can get a very accurate feel for the dose and use it very accurately. To achieve this, always measure out how many grams you’re ingesting, that way you can easily determine which range suits you. At last, we conclude that the effect of eating cannabis seeds(tend to) last longer than smoking.
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