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Jo Harvelle

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  1. Alzheimer’s disease (AD) is the most common form of dementia. It is a progressive and degenerative disease that affects the patient’s memory, thinking and ability to interact socially. It affects about 1 in 10 people over 65 years, and almost 1 in 4 people over 85 years. Cannabidiol (CBD) is one of the hundred compounds found in the cannabis plant that belongs to a class of chemicals called cannabinoids. However, CBD does not produce any psychoactive effects like the other known cannabinoid called THC. CBD possesses neuroprotective, anti-inflammatory, and antioxidant properties. These properties can be therapeutically beneficial for reducing the cognitive and functional impairment that occurs with Alzheimer’s disease.
  2. Great Information. But also provide a link to your post.
  3. Cannabis is such a fantastic plant where cannabinoids and terpenes work synergistically, and this is collectively called full-spectrum extract. While THC has euphoric effects, CBD and terpenes are known for their non-psychoactive effects. Hence, the impact of a particular cannabis strain can vary dramatically depending upon the ratio of the two active cannabinoids. You might have noticed while visiting a dispensary that Indica or Sativa flavor profile organize the cannabis products, price per gram, and also via THC: CBD content. But, still very few people have any information about the benefits of the correct THC: CBD ratio. Hence, instead of just focussing on the dosage of cannabis-based on milligrams or percentage, people are considering ratios as the basis for choosing a strain for medical purposes. CBD vs. THC Marijuana contains over 100 types of chemical compounds called cannabinoids. Out of these cannabinoids, CBD and THC are known for their interaction with the body’s endocannabinoid system receptors. They both have different medicinal properties as well as effects on the body. The difference lies in the way they interact with the receptors in the body. While THC binds CB1 receptor favorably, CBD acts as an antagonist to the receptors and also partially blocks the CB1 receptors, thus reduces the euphoric effects of the THC molecules. THC is known for its euphoria while acting as an anti-inflammatory, anti-emetic, and an analgesic. However, CBD shares some of these properties but, also is known for its anti-seizure, anti-anxiety and antipsychotic properties. Some studies even have reported that CBD is thought to enhance anti-cancer and pain reducing properties of THC. Therefore, depending on your particular condition, you will respond to the different CBD: THC ratios present in the strains. CBD: THC ratios and their benefits CBD:THC 0:1 This is a THC dominant strain where the person will experience intense psychoactive effects. The strains with such ratios are known for uplifting the moods, thus making the person happy. These strains can help induce appetite, reduce inflammation with relaxing effects. Strains with high THC content are Gorilla Glue by Zamnesia with THC content of 25%, and Girl Scout Cookies is loaded with 22% of THC. CBD:THC 1:2 This type of strain produces a calming sensation with reduced cases of anxiety. Thus, these type of strains can significantly reduce the euphoric effects of THC with the help of CBD which acts as an antagonist. These strains can help in dealing with the number of conditions like chronic pain, anxiety, stress, insomnia, migraines, and muscle spasms with the help of synergistic benefits that THC and CBD provide. Strains with less THC with counterbalancing CBD levels are Blue Widow, OG Kush. CBD:THC 1:1 Research so far supports strains with this kind of chemical makeup as these strains provides the most effective medicinal properties for a different number of disorders and their associated symptoms like insomnia, fibromyalgia, autism, chronic pain, spasticity, reduced appetite, and skin diseases. This kind of ratio provides the maximum relaxing effects with minimal euphoria. Strains known for this particular ratio are Cannatonic, Sweet Tooth Auto, Critical Mass CBD. CBD:THC 2:1 or 3:1 This type of strain is ideal for the patients who wish to avoid the euphoric effects of THC. This ratio is suitable to combat autoimmune disorders, gastrointestinal issues like Crohn’s and colitis, arthritis, and psoriasis. The strains which are known for their calming effects with high CBD content are Kama Kush CBD, CBD Critical Cure, and Cheese Autoflowering. CBD:THC 1:0 This is the CBD dominant strain with enormous medicinal potential. The ratio is very rare in reality. However certain strains are close to this ratio such as CBD Therapy with 10% CBD and just 0.5% THC, Candida (CD-1) with 20% CBD and only 1% THC.
  4. The benefits of Marijuana has changed the public opinion about the product. People are now becoming more aware of its positive effects and thus, demanding its legalization with 64% votes across the country. Till yet, medical marijuana is legal in 29 States while recreational cannabis is legal in 6 US States. The growing demand for the product by the public has some good prospects for the establishment of the cannabis industry. The global market for cannabis, worth about $7.7 billion is expected to reach $31.4 billion by 2021. But, it's still not legal at the Federal level, which makes it difficult for the industrialists and the businessmen to operate cannabis business in the country, as many banks don't want to work with them or provide any finance to run their business in the fear of any legal prosecution. Due to this, cannabis dispensaries don't even get access to use credit or debit cards. The cannabis industry needs some financial solutions to work, under no risk factors and to be capable enough to compete with other sectors. Along with this, it is also necessary to prevent theft, product diversion, and other criminal activities and to maintain the track of inflow and outflow of capital used in doing business. To resolve all these issues, the market has come up with a solution; Cryptocurrency. It is a digital currency that is made from code and has no physical form. It is controlled by a decentralized network of associates. There is a use of encryption for the creation of the currency and verification of transactions. It has resolved the big problem of the cannabis industry, i.e., banking. Its network also helps in keeping a record of every transaction and uses a blockchain to maintain an irreversible record of deals. Forms of Marijuana Cryptocurrencies Bitcoin was the first cryptocurrency invented with the price, $0, and now its value is around $188 billion. After its successful circulation in the market other Cryptos came out, like Ethereum with a market cap of $103 billion and a price of more than $1000. Other existing cryptocurrencies are Ripple, Bitcoin Cash, Cardano, Stellar, and Litecoin. Some cryptocurrencies are made especially for specific industries like the Cannabis Industry. They are designed to make marijuana transactions more secure. These include Potcoin, Hempcoin, Marijuana coin, Sativa coin, Canna coin, Dope coin and Paragon. Among these, the most famous and the top-ranked marijuana-focused cryptocurrency is Potcoin with the market cap of $51 million. With the emergence of Cryptocurrency, the consumer has an option to use it to buy marijuana. He or she can exchange their crypto with the dispensary to buy their cannabis product. To obtain a Cryptocurrency, the consumer requires to show a valid ID. There is also a limit for purchasing it to prevent money laundering. Benefits of Cryptocurrency There are many benefits of using Cryptocurrency in the marijuana industry and dispensaries, such as: It provides security by maintaining lesser cash in the dispensary. Also, the Cryptocurrencies can be tracked easily, thus, there is a reduced risk of robbery or theft. It maintains complete privacy of the user's identity since all the transactions take place digitally. It is easy to maintain in keeping the transparency in the flow of the product from the marijuana industries to dispensaries to the user with Cryptocurrency. It holds every record of the cultivation, distribution and the selling of the product. Moreover, it provides convenience to the customer who avoids carrying cash to buy marijuana, thus, increasing the business and profit of the cannabis enterprises. Disadvantages of Cryptocurrency The concept of the Cryptocurrency is somewhat new among a majority of the people. Many people are still not able to understand the idea behind it and consider its use to be risky. People are uncertain about its future, which stops them from opting for this cashless option for their cannabis purchase and businesses. Stakeholders and businessmen are worried about the future of Cryptocurrency. Some economists predicted that soon, a government regulation will weaken the Crypto market. With these limitations, many don't want to stick to it as a hope for the marijuana industry. What's Next? It is currently difficult to predict the future of Cryptocurrency as the topic is new to a lot of people, including the industrialists. Possibly, if more States legalized the marijuana use, the Federal government will either leave the decision for the States or enact a strict legislation for its regulation. Also the awareness of the Federal government about Cryptocurrencies and their increasing demand with the growth of the cannabis industry may introduce legalization that would allow marijuana industry to use the banking services soon.
  5. The question is, how do you store cannabis in a way that could extend its longevity while maintaining the vigor and freshness? Experts have described different methods. However, here are some time-proven methods that are easy and inexpensive and require very less equipment. View this video for proper information:- How to Store Cannabis Properly and Make it Last for Years.mp4
  6. People undergoing chemotherapy often experience various side effects which can be detrimental to their health. In chemotherapy drugs are induced in the person’s body intravenously, and their major role is to attack the growing cancer cells. These drugs can even kill the healthy cells. A person undergoing chemotherapy often experiences nausea, vomiting, hair loss, loss of appetite, swelling in the hands and feet and many more. Marijuana offers immense health benefits and provides relief against various medical ailments. Cannabinoids like THC and CBD present in the cannabis is linked with medicinal properties. Studies suggest that CBD may help an individual manage and control various side effects of chemotherapy. If you are a medical patient, you can consume cannabis only if you have a medical marijuana recommendation. People of Los Angeles can take get their medical marijuana card in Los Angeles from the online medical card. Onlinemedicalcard is a clinic where people can get their mmj card online within a few minutes directly to their inbox. With your mmj card, you can use CBD with chemotherapy.CBD won’t get you high but provides relief against various chemotherapy side effects. Neuropathic pain: Cancer patients may experience neurotic pain because of their cancer or treatment. It is highly common among the patients undergoing chemotherapy and occurs mainly due to nervous system damage. Studies have revealed that CBD can treat neuropathic pain without affecting the nervous system or decreases the efficacy of the treatment. A clinical trial revealed that cancer patient experienced less pain after taking THC and CBD for 2 weeks. Nausea and Vomiting: CBD offers anti-emetic and anti-nausea properties that make chemotherapy more tolerable, and the chances of the success of it increase. Preclinical studies indicate that CBD can treat both nausea and vomiting which are the side effects of chemotherapy and other treatments. Swelling: Bloating is caused due to the retention of fluid in the body. This can usually be seen in face, hands, feet, and ankles. In rare cases, swelling can be the result of the allergic reaction to chemotherapy medications.CBD has immense anti-inflammatory properties which makes it a great choice for reducing swelling. It interacts with the CB2 receptors of the endocannabinoid system. Emotional well being: Getting a chemotherapy treatment seems like a lifetime, and this develops anxiety and depression in the cancer patients.CBD has the potential to treat various mental illnesses like depression and anxiety. Moreover, CBD influences specific receptors present in the endocannabinoid system which manage depression and anxiety. Stimulates Appetite: As discussed above that CBD stops nausea and vomiting and helps in stimulating the appetite of the person. Now, after knowing about its properties and benefits you want to give it a try. You can choose from the wide range of CBD products like edibles, oils, tinctures and more. But, first, you require a medical marijuana card to consume marijuana legally in Los Angeles. So, step ahead and get in contact with the licensed physician and pay a small amount and get your medical marijuana card online from the online medical card. The doctor will recommend once you qualify for an MMJ card. You will get your card delivered to your mail within 10 mins without any hassle. After getting this you can purchase cannabis from a licensed dispensary.
  7. “Marijuana is a time-tested herb that affects the brain most and its results can be seen immediately or within 10-15 minutes. It’s not disputed that despite having certain intoxicating or drunkenness type effects, marijuana also carries medicinal properties. These medicinal properties have the potential to cure chronic mental ill-health conditions. In a recent research conducted at the University of British Columbia, the Scientists have found marijuana to have potentials for using it for mental health. A large number of the Patients have benefitted themselves by using Medical Marijuana Cards for the treatment of mental disorders, including psychosis, stress, depression, anxiety, PTSD and many more.” Practically, marijuana, alcohol, and caffeine all affect our brain the same way. For a time being, all the three make us high, keep us focused on a single thought that is reflected in the mind and hamper the brain’s ability to function normally. Of the three, only marijuana is believed & tested to have certain positive effects that are beneficial for the health. Marijuana is one of the oldest crops that were cultivated in Central Asia, China and Egypt. Ancient inhabitants started using marijuana as a narcotic drug at least 10,000 - 15,000 years ago. Evidence related to using this herb for medical purpose dates back to 2500-3000 BC back. Cultivation and medicinal uses of marijuana are also mentioned in the Ancient Indian Texts. But, there is hardly any reference that shows if any of the kingdoms had ever restricted cultivation or using marijuana, whatever be the purpose. However, after researching on the bad effects, this herb became ill-famed and invited State restrictions across the world. There has been a long ongoing debate on the issue, whether marijuana affects mental health. There has been neither a consensus nor any conclusion. People stand divided and stay swinging one side or the other. The second line of the intelligentsia that includes Doctors, Scientists & Scholars, appear to be firm in their opinion. They count negative effects of the marijuana on the mind and general health of the people more. Unfortunately, all the studies and researches were conducted on the addicted recreational smokers, but not on the medical marijuana users. The reason is, marijuana has been categorized as a Schedule-1 Drug. Legally, without getting State’s permission, it’s not possible to conduct tests on medical marijuana for human use. The process to get the permission is tedious, time-consuming and troublesome. In other words, scientific studies on the medical marijuana are very small or insignificant for arriving at some conclusive results. Use Of Marijuana in Psychiatric- Mental Health Conditions: In about 29 States, riding on the public demand, as well as political will, marijuana has been allowed for the treatment of several mental ill-health conditions. These include simple stress to PTSD, Anxiety, Insomnia, Depression, Alzheimer Disease etc. There are a few another Brain-related disease that directly results in mental ill-health. These include Brain Tumors, Blood Clots in Brain, Brain Inflammation due to Stress, and Encephalitis etc. Of these, Alzheimer Disease is one of the most deadly diseases in America. Epilepsy is another disease, though, can’t be directly stated to be a mental ill-health, and certainly affects the mental health during the course of the seizures. Use of Medical Marijuana in the treatment of these illnesses and other Psychiatric conditions has shown significant results. The patients who used medical marijuana for mental ill-health related issues reported getting a significant relief. By now, it has become clear that marijuana gives very good results in the conditions of depression, insomnia, and anxiety. How Does Medical Marijuana Affect Our Mind? Marijuana contains more than 100 compounds. Of these, more than 60 belong to Cannabinoids family. They got their name from the Cannabis. The scientists say that our internal system responds to the cannabinoids biologically. THC Cannabinoids which are found in the cannabis, have an almost same structure as that of natural cannabinoids available in the endocannabinoid system in our body. A natural communication system works between our brain, our organs and other parts of the body. When these natural cannabinoids are damaged, the cannabinoids found in cannabis can make up the deficiency of natural cannabinoids. According to the studies and research conducted at the prominent Universities in America and Canada, the Substance has been found to have the potential for curing the mental ill-health conditions. Researchers found that the marijuana had benefited the patients with stress, depression, anxiety and PTSD issues. California, Marijuana & Medical Marijuana Cards: In the contemporary times, California was the first State to legalize Medical Marijuana in the year 1996. Relying upon the undisputed reports on some of the beneficial effects, the State opened using this herb for the medical purpose and treatment of Stress, Anxiety, Depression, Chronic Pain Management and a few more conditions. The use of marijuana for medical purpose is channelized via Medical Marijuana Cards. Since then, despite facing severe criticism, the use of marijuana has survived in the California law. Rather, the herb has also become legal for recreational use, of course, subject to a few conditions. Why Should You Have A Medical Marijuana Card? From 1 January current year, use of recreational marijuana has become legal in the California State. The new cannabis law promises more benefits to the Medical Marijuana Users than the recreational users. Medical Marijuana users can carry it as per their need. They can grow more cannabis plants in their homes. Moreover, use of cannabis has been yet illegal at Federal Level. Only 29 States have legalized the use of marijuana, either for medical purpose, or recreation. If you are travelling to a non-legal State, your medical marijuana card can save you from Police harassment and embarrassments. These cards are valid for only 1-year. If you have been using medical marijuana previously, then do not forget to get your Medical Marijuana Card before its expiration date. In California, the Doctors are licensed by the State, as well as Local Health Dept. for recommending medical marijuana. You need a Doctor’s evaluation for getting a medical marijuana card. Physical clinics as well as Online Marijuana Clinics, are providing marijuana recommendations. Consulting an online doctor is convenient and time saver too.
  8. Thanks for your information.
  9. Stoners often indulge in the act of wake and bake. Cannabis gives the euphoric feeling along with the psychoactive effects. Cannabis recreational users who consume cannabis occasionally don’t have to worry much about the dosage of cannabis. But, the people who are dependent on cannabis for the whole day need to worry. As a medical cannabis user, there may be several questions pondering your mind, like, “How much cannabis should I take, and at what time.” Here, we have highlighted some points for the people who need to consume cannabis throughout the day. Edibles: If you don’t like to smoke you will probably be wondering, “Can I switch to edibles?” But remember, it is not a good option to introduce yourself to cannabis. Edibles are much stronger and have a long-lasting effect than vaporizers. Even an experienced cannabis user should consume micro-dose of the edible. Moreover, the best way to have edibles is to take it slowly and choose edibles having low amounts of THC, say 5mg or less every 1-2 hours and immediately stop when you don’t feel much pain. Edibles having a massive amount of THC are advisable to a cancer patient, but you should consult your doctor before ingesting even a single dose. CBD-Rich Products: Cannabinoids found in the marijuana imitates the endocannabinoids which are made by the body. CBD-rich products act as a buffer which modulates THC effects. The reason behind this phenomenon is that CBD is a negative modulator of CB1 receptors. However, this fact is still under consideration as human trials have shown different results. For instance, CBD may help the effect of THC to last longer, and vice-versa or may not have any significant effect. On the other hand, Tetrahydrocannabivarin (THCV) is another cannabinoid that is a negative modulator and has a high affinity to CB2 receptors. Don’t Operate Cars or Machinery: Cannabis affects the reaction time and the motor control, therefore, you should not operate cars or any other bulky types of machinery while consuming cannabis. Cannabis and the Workplace: No workplace entertains the use of cannabis, and you cannot risk your job. So, it is better to refrain yourself from using cannabis at the workplace. You can perhaps use it before or after your work. How to Prevent a Bad Experience? Using the products which have less amount of CBD can help in overcoming the adverse effects of THC. Chewing black peppercorns, which contains the terpenoid beta-caryophyllene can relieve you from adverse effects; it interacts with cannabinoids, calms and keeps you hydrated.
  10. Summary: Are you a resident of California and you want to become a legal grower of medical marijuana? Then, first get a doctor's recommendation to cultivate it. You can grow up to 99 plants with the State Grower's License. But, how do you get the permission to cultivate marijuana in your state? Learn it here and get a license to grow more. Marijuana laws in California California approved Proposition 215 in 1996. Under this law, a person aged 18 or above are eligible for a doctor's recommendation to consume medical marijuana in the State. With an MMJ card, you are allowed to possess up to eight ounces of dried flower. You can also cultivate up to six mature or twelve immature plants. Growing more than that is punishable under the law. Also, the State under SB 420 allows a band of dispensaries to grow 99 plants at the same time in a Non-Profit capacity. Why you need a Grower's License Medical Marijuana recommendation allows the cultivation of only six mature or twelve immature plants. However, for treating many medical conditions like chronic pain, and cancer, this number is not enough. To increase the limit of cultivation you can engage in at a time, there is a need for you to get a Medical Marijuana Grower’s License in California. It allows you to grow up to 99 plants in an enclosed area. How to get a doctor's recommendation for Grower's License Like MMJ card, for grower's license also, it is essential to have a doctor's recommendation. To get it, one has to visit a medical marijuana certified doctor in California. The doctor will then evaluate your health. If on evaluation he considers more marijuana a necessity for your cure, he will approve your requirement. The doctor can then recommend the number of plants that will meet your need. But, the number of plants he can recommend cannot be more than 99 plants in number. Getting a permission to cultivate marijuana allows you to grow marijuana for your own use. Note that you are not allowed to sell the product or use it for earning any profit. How the grower's license helps you to get a better product There is a lot of differences between purchasing the product and growing your own. With a good knowledge of the cultivation methods, you can be able to produce a healthy plant. So, meet your requirement with an exponential yield of good Cannabis by growing your own medical marijuana. Grower's License only provides you the permission to cultivate Cannabis in your State. There is still a possibility of Federal prosecution for using marijuana in the State as it is illegal at the central level. So, always get a doctor's recommendation before using or cultivating it in the State.
  11. Jo Harvelle

    CBD oil

    For medical/therapeutic purposes, the majority of CBD users tend to prefer to administer an oil tincture sublingually (under the tongue) with either a spray or dropper bottle. This is because CBD is most efficient and versatile when absorbed directly into the bloodstream. If you take a 5 mg dose in the morning, for instance, and notice little to no positive effects, then up the dosage to perhaps 8 or 10 mg in the afternoon/evening, and see where that takes you. It is one of the best medicine. It is not particularly dangerous. Don't make life decisions, and don't worry about everything else. By using CBD oil Stay fit and healthy.
  12. California MMJ cardholders for instance can buy up to 8 ounces of weed per day, while recreational users can only buy 1 ounce per day. While of course no one out there is burning through 8 oz of weed in a single day (or are they?), this can be a pretty significant advantage for a couple of different reasons. Another reason is in terms of product specificity. Any medical weed user will likely tell you that they have a specific strain (or at least a specific product) that they find works best for them. With the advantage of being able to buy large quantities at a time, you can virtually ensure that you’ll always have access to your favorite strain, rather than driving to the dispensary and hoping that they’re not sold out of whatever it is that you need. Yet another advantage that medical weed users have over recreational users is that, at least in most states, there are laws that allow MMJ users to smoke (or otherwise consume) cannabis in public. All in all, whether or not it’s worth it for you to hang on to your MMJ card and keep renewing it year after year will determine on a few different things. The main thing of course is how much weed you actually use. If you consume anywhere around an ounce per month, it will likely be in your best financial interest to hold onto the medical card, rather than buying recreationally.
  13. With the passing of the Proposition 215 in 1996, California with the highest population, became the first state to approve medical marijuana legal use. At that time only 55% population favored the legalization of medical marijuana, but today more than 60% of adults in the State are enjoying its benefits. Presently, 29 states had sanctioned the approval of the legal use of medical marijuana. Medical Marijuana Industries in the state Medical marijuana industry in California is huge. Investors and industry-watchers are smelling money from its future business, predicting that medical marijuana would deliver multi-billion dollars in the coming years, which is $20 billion in 2020. According to Ackrell Capital, California’s legal medical marijuana industry has already topped $3.8 billion. However, with the flourishing of new ancillary services in legal support, marketing, business development and many others, it is pushing a massive demand for employees to meet the needs of a rapidly expanding consumer marketplace. For the cultivation of medical marijuana, the state has set around 3500-4500 acres of land for cultivators and manufacturers of medical marijuana. According to Troy Dayton, the CEO of ArcView, California generated $2.7 billion in medical cannabis sales in 2015. It will contribute to 62% of all medical cannabis sales in the U.S. in 2015, which is as per the estimation made by New Frontier and ArcView expected to climb to $ 6.6 billion in 2018. This number implies that industry is the decisive contributing factor in the economy of the state. However, the growth of medical marijuana industry will see a decline for the first three to five years and is expected to again provide the business of $24 billion by 2025 with an annual growth rate of more than 17%. The setting of the new industries of medical marijuana has a projected value of $7 billion. The business of this industry will provide the government with hundreds of millions of dollars thus providing the state with $1 billion in a year. California’s cannabis market will now transit into the fully regulated market, complete with comprehensive, state and local level permitting level with the passage of assembly bill number 266 (MCRSA) and enactment of the prop. 64 (AUMA). According to the report from New Frontier Data, it is considered that by 2020 the legal cannabis industry will be the gateway to opportunities for many people and provide more than a quarter of a million jobs. This year 2018 is a bumpy one for California as more shops would be opened, more stringent regulations would likely to be put in place which would have an impact on the strains like Sweet Skunk, Trainwreck, and Russian Assassin.
  14. HIV: A cause for AIDS HIV stands for Human Immunodeficiency Virus which can lead to Acquired Immunodeficiency Syndrome; AIDS. It makes the body's immune system weak and thus hinders its ability to fight against infections. A weak immune system makes body's cell more susceptible to develop cancer, leukemia, pneumonia, liver failure and other life-threatening conditions. The virus has infected around 35 million people in the world since 1980. Of these, about 1.1 million of people in the US are living with AIDS presently. The disease has caused the death of around 20000 Americans in the year 2014. This draws the attention of the researchers to find and develop the best alternative to lessen its effect. The activity of the HIV in the human body A virus once enters the human body makes several copies and enter into almost every part including bone marrow and brain. Thus, it does not leave the patient's body completely, even with treatment. However, its effect can be decreased by using various drugs available. Antiretroviral (ARV) drug are prescribed to suppress the activity of the virus. But these drugs do not affect the HIV copies residing in the brain and also have some considerable side-effects associated with its long-term use like nausea, vomiting, diarrhea, weakened bones, and neuropathic pain. Cannabis as an approach towards treating HIV/AIDS. The researchers are looking for the better solution to reduce or suppress the activity of the virus in the body. Some scientific studies revealed that marijuana could manage the symptoms and effects associated with HIV. They are now moving forward to study the favorable effects of cannabis on HIV patients. They are able to design a drug using cannabis that targets an area in the body where the ARV fails to reach. People infected with HIV in the US are depending more and more on cannabinoid-based therapies to reduce the effect of HIV infection. One out of three patients is opting cannabis to fight HIV/AIDS due to its incredible effect. It also helps in treating the conditions associated with ARV consumption like depression, nausea, pain, sleeping problems and weight loss. How does the cannabis work? Plasmacytoid dendritic cells (pDC) are the immune cells that are responsible for the activation of B-cells (antibody producing cell). They play a crucial role in host antiviral immune response. On interacting with HIV, its number decreases in the blood. This results in increasing the activity of the virus and ultimately it progresses towards AIDS. THC in cannabis combat the effect of HIV by dampening pDC activation. This suppresses the pDC function during the early phase of interaction between the host and the virus. Thus, preventing the condition from getting worse. Before the legalization of cannabis in the state of US, the doctors used to prescribe a synthetic pill Marinol, containing THC to reduce the effect of HIV. But the medicine lacks other components of the plant like cannabinoids and terpenoids that play their significant role in decreasing HIV/AIDS effect. Thus, inhaling cannabis proved to be more fruitful for the patients. It also produces a large number of CD4 and CD8 cells in the body that fights against the virus in the body. Cannabis not only helps in reducing the symptoms and side effects of HIV but also show some promising effect in inhibiting the progression of HIV/AIDS. Cannabis also increases the frequency of appetite hormones in the blood of HIV patients. One of the studies published in 2004, proves that there is a substantial increase in food intake of the HIV/AIDS patient who smokes cannabis around four times a day.
  15. What can be worse than tossing and turning in bed the whole night? Still, 1 in 10 people is losing their sleep due to insomnia. Insomnia is a sleep disorder which causes difficulty in falling asleep. It can be of two forms of acute or chronic. Usually, acute insomnia lasts for a night to few weeks whereas, chronic insomnia can last for a month or longer. This condition occurs due to stress, anxiety, jet lag or from a particular medication. What are the symptoms of insomnia? Irritability, depression, and anxiety Waking up in the middle of the night Feeling sleepy throughout the day Treatment for Insomnia: It is usually treated with prescribed medications, counter medications and even with cognitive or the behavioral treatment methods. Still, many people suffer from this sleeping disorder. Several types of research have been carried on marijuana, and it has been found that marijuana can help a person falling asleep when taken before bed. These days marijuana is not only restricted to the stoners, but it is also for the people suffering from lack of sleep and chronic pain. Many people in legalized states are using medical marijuana as a sleeping aid. Scientists have proven that cannabis boosts the immune system and revives the body. It has been found that CBD-enriched cannabis like tinctures and potent oil enhances sleep. Moreover, edibles let people sleep for at least 10 hours. You can double the effect of cannabis when you consume it with other herbs like hops, chamomile, and lavender. These herbs contain terpenes which enhance the sedation effect. According to the study conducted in Canada on 104 HIV -positive adults, two-thirds endorsed the use of cannabis for sleep among other benefits. Also, Harvard Medical school stated that marijuana has a relaxing effect. Findings published in a 2015 issue of the Journal Scientific reports that marijuana has a lower risk of mortality than alcohol and cigarettes. Moreover, studies have indicated that cannabis has the potential to combat stress and depression which are the primary reasons behind sleep deprivation. 2013, the study revealed that marijuana users had less difficulty falling asleep and have more daytime sleep the following day as compared to non-users. Marijuana also found helpful in sleep apnea which is the condition where person’s breathing is interrupted during sleep.THC calm or stabilize sleep apnea. Not only this, but people with PTSD (post-traumatic stress disorder) can also benefit from cannabis regarding sleep. A 2009 study found that patients those were administered with synthetic THC sleep longer and had a quality sleep and experienced fewer daytime flashbacks. Marijuana can relieve pain, and research shows that marijuana has improved the quality of sleep among the people suffering from chronic pain. How marijuana aids in sleep? Marijuana impacts your sleep in many ways. The compounds, cannabinoids present in cannabis mimic the activity of chemical found in the brain and hence regulates sleep. Moreover, cannabis can affect the progression and the length of a sleep-wakeup cycle of the individual. It usually changes the way you sleep. Studies have shown that THC can increase the amount of slow-wave sleep also known as deep sleep in an individual. It is believed that the person experiences sleep deprivation due to lack of slow-wave sleep. Things you need to consider: As marijuana induces sleep but, you still need to balance your dose.THC makes you drowsy and helps you to fall asleep whereas, CBD keeps you awake. So, you need to choose a strain that has higher THC value. Sativa strains generally have high CBD content than THC whereas, indica strains are rich in THC. Moreover, Sativa strains are known for their uplifting and high efficiency, on the other hand, indica induces sleep. Marijuana impairs REM sleep; it is sleeping stage where you experience dreams. If you use cannabis at night, you might notice fewer dreams. Moreover, you should expect some hangover symptoms if you smoke cannabis late at night. People who use cannabis occasionally experience quality sleep, but the person who smokes regularly lacks sound sleep. In the end, we would like to say that smoking cannabis at night might help you to combat insomnia. But using it multiple times a day disrupts sleep. So, it ’s better to have less when it comes to sound sleep.

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